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Pyometra is a uterine infection that accumulates pus in the uterus.


  • purulent vaginal discharge
  • abnormal thirst (polydipsia)
  • abnormally large amounts of dilute urine (polyuria)
  • increased aggressiveness
  • depression, lethargy, and anorexia


Pyometra is usually reported shortly after a rabbit delivers her young.[1]:476

It can also be a manifestation of Pasteurella multicoda transmitted during coitus.[2]:456 Other bacterial causes of pyometra in rabbits include the following:[3]

  • Staphylococcus aureus (most common)
  • Chlamydia
  • Listeria monocytogene
  • Moraxella bovis
  • Actinomyces pyogens
  • Brucella melitensis
  • Salmonella spp.

Further reading


  1. Mitchell, M. A., & Tully, T. N. (2016). Current therapy in exotic pet practice. Retrieved from
  2. Varga, M. (2013). Textbook of rabbit medicine. (2nd ed.).
  3. Oglesbee, B. (2011). Blackwell's five-minute veterinary consult: Small mammal. (2nd ed.).