Adrenal disease

Adrenal disease occurs when the adrenal gland produces either too much or too little of certain hormones.

Symptoms
Generally, neutered rabbits will act like they are intact with excessive marking, humping, chasing, and unusual aggression. It has been predominantly reported in elderly rabbits over 6 years of age. In does with adrenal tumors, enlargement of the clitoris can be noted.

Diagnosis
In the US, the University of Tennessee College of Veterinary Medicine Diagnostic Laboratory Services offers an adrenal panel for castrated and spayed rabbits.

Treatment

 * Surgery
 * Lupron
 * Deslorelin

Experiences

 * Buns of Steel. (2021). Fluff's story with a fatal adrenal tumor
 * Elisabetta Mancinelli. (2016). Adrenal gland disease in rabbits
 * Katherine Baine et al. (2014). Elevated Testosterone and Progestin Concentrations in a Spayed Female Rabbit with an Adrenal Cortical Adenoma

The following are a few discussions on the topic:


 * House Rabbit Society. (2022). Using Deslorelin implants to manage rabbit hormones
 * House Rabbit Socity. (2021). Has anyone dealt with adrenal gland disease in bunnies?
 * House Rabbit Society. (2020). Anyone experience adrenal disease before?