Uterine cancer: Difference between revisions

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Uterine cancer, also known as uterine or endometrial adenocarcinoma or uterine neoplasia, is a serious risk for intact female rabbits. Uterine adenocarcinoma is a gland-like malignant type of tumor that arises from the secretory tissue that lines the inner cavity of the uterus. The tumors usually arise from the endometrial or inside layers of the uterus.

Reported incidence rates of uterine cancer in rabbits have ranged from 50%-80% in female rabbits over 4 years of age, especially in certain breeds.^[1] For this reason alone, rescues and veterinarians strongly recommend the spaying of female non-breeding rabbits.

Symptoms

Intact female rabbits over 3-4 years of age are most at risk.

Blood in urine.
Vaginal discharge stained with blood.
Cysts in the mammary glands and mammary growths.
Cloudy fluid that may come from the mammary glands.
Behavioral changes, including aggressiveness.
Lethargy, inability to eat, and pale mucous membranes.
Abdominal masses

Experiences

Below are some anecdotes about encounters with uterine cancer in rabbits.

Great Western Exotic Vets, May 2011 - Uterine Adenocarcinoma in a Rabbit
Miriam's Bunnies, Onyx's Story
Rachel Cama-Lekx, Eve's Story: The Consequences of Not Spaying
Reddit, /r/rabbits, Miss Celie will live to be an old bunny, thanks to the /r/rabbits community (more in comments).
RabbitsOnline, Uterine Cancer ... Worried and Need some Advice
Facebook, Sweetie's Journey, Stories about other rabbits that had/have uterine cancer

References

↑ British Small Animal Veterinary Association, Policy Statement on the Neutering of Rabbits

[bsava-1] British Small Animal Veterinary Association, Policy Statement on the Neutering of Rabbits

[1]

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 == Further reading ==
-* PetMD, [http://www.petmd.com/rabbit/conditions/reproductive/c_rb_uterine_adenocarcinoma#.UHZcbsXA-So Uterine Adenocarcinoma in Rabbits]
+* PetMD. [http://www.petmd.com/rabbit/conditions/reproductive/c_rb_uterine_adenocarcinoma#.UHZcbsXA-So Uterine Adenocarcinoma in Rabbits]
-* St. Francis Animal & Bird Hospital Library, [http://www.stfrancisanimalandbird.com/ResourcesLibrary/?page_id=244 Rabbit Uterine Adenocarcinoma]
+* Wildpro. [http://wildpro.twycrosszoo.org/S/00dis/Miscellaneous/UterineAdenocarcinomaRabbit.htm Endometrial Adenocarcinoma and other Uterine Neoplasia in Lagomorphs]
-* Rabbit Welfare Association & Fund, [http://www.rabbitwelfare.co.uk/resources/content/info-sheets/uterine.htm Uterine cancer in the doe: What's the story?]. Updated November 2004.
+* House Rabbit Society. [http://www.rabbit.org/care/bibliography.html Medical Bibliography]
-* Wildpro, [http://wildpro.twycrosszoo.org/S/00dis/Miscellaneous/UterineAdenocarcinomaRabbit.htm Endometrial Adenocarcinoma and other Uterine Neoplasia in Lagomorphs]
+* Vetstream. [https://www.vetstream.com/treat/lapis/freeform/uterine-adenocarcinoma Uterine adenocarcinoma]
-* House Rabbit Society, [http://www.rabbit.org/care/bibliography.html Medical Bibliography]
+* Dr Jay E. Hreiz. (2013). [http://msue.anr.msu.edu/uploads/219/38708/Uterine_Adenocarcinoma_in_Rabbits_Jan-Feb_20130001.pdf Uterine Adenocarcinoma in Rabbits]
-* FVMA's 82nd Annual Conference, [http://www.fvmace.org/FVMA%2082nd%20Annual%20Conference/Proceedings/Rabbit%20Neoplasia.html Rabbit Neoplasia]
-* Vetstream, [http://www.vetstream.com/lapis/Content/Freeform/fre00002.asp Uterine adenocarcinoma]
-* The Merck Veterinary Manual, [http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/171350.htm Neoplasia]
-* Domestic Rabbits Magazine (Jan-Feb 2013), [http://msue.anr.msu.edu/uploads/219/38708/Uterine_Adenocarcinoma_in_Rabbits_Jan-Feb_20130001.pdf Uterine Adenocarcinoma in Rabbits]
 The following are scientific papers analyzing the statistics of cancer in intact female rabbits.
-* Harry S. N. Greene, [http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1959.tb44573.x/abstract Adenocarcinoma of the uterine fundus in the rabbit.], 1959.
+* Harry S. N. Greene. (1959). [http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1959.tb44573.x/abstract Adenocarcinoma of the uterine fundus in the rabbit.]
-* Theodore H. Ingalls, William M. Adams, Max B. Lurie and Johannes Ipsen, [http://jnci.oxfordjournals.org/content/33/5/799.short Natural History of Adenocarcinoma of the Uterus in the Phipps Rabbit Colony], 1964.
+* Theodore H. Ingalls, William M. Adams, Max B. Lurie and Johannes Ipsen. (1964). [http://jnci.oxfordjournals.org/content/33/5/799.short Natural History of Adenocarcinoma of the Uterus in the Phipps Rabbit Colony]
 * E. Cotchin, [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071320/ Spontaneous Uterine Cancer in Animals], 1964, pg. 216-218.
 * Th. A. M. Elsinghorsa, H. J. F. Timmermans & H. G. Ch. J. M. Hendriks, [http://www.tandfonline.com/doi/abs/10.1080/01652176.1984.9693937 Comparative pathology of endometrial carcinoma],  1984.
 * Hablolvarid, M.H., Golami, M.R., Moharami, M., [http://www.sid.ir/en/VEWSSID/J_pdf/83520060308.pdf Uterine Adenocarcinoma in a Rabbit], 2006.
-* B. Walter, T. Poth, E. Böhmer, J. Braun, U. Matis, [http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=00424900&AN=48318411&h=JisfzAdW36w9L3Pg4OCMXIcgcZgp7b6WGUg%2fZ6OeSjMtxYz1PcVIDTgPUxpkFxGGsVxJvbKAOLX1W8D4djXlPg%3d%3d&crl=c Uterine disorders in 59 rabbits.], 2010.
+* B. Walter, et al. (2010). [http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=00424900&AN=48318411&h=JisfzAdW36w9L3Pg4OCMXIcgcZgp7b6WGUg%2fZ6OeSjMtxYz1PcVIDTgPUxpkFxGGsVxJvbKAOLX1W8D4djXlPg%3d%3d&crl=c Uterine disorders in 59 rabbits.]
-The following are articles from rabbit breeders.
-* Bucky's Bunny Barn, [http://buckysbunnies.tripod.com/UC.html Uterine Cancer in Rabbits]
-* The Bunny Box, [http://thebunnybox.weebly.com/1/post/2013/01/doe-heath-check.html Doe Heath Check]
 == See Also ==