Uterine cancer: Difference between revisions

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'''Uterine cancer''', also known as uterine or ''endometrial adenocarcinoma''' or '''neoplasia''', is a serious risk for intact female rabbits. Uterine adenocarcinoma is a gland-like malignant type of tumor that arises from the secretory tissue that lines the inner cavity of the uterus. The tumors usually arise from the endometrial or inside layers of the uterus.
'''Uterine cancer''', also known as uterine or '''endometrial adenocarcinoma''' or '''uterine neoplasia''', is a serious risk for intact female rabbits. Uterine adenocarcinoma is a gland-like malignant type of tumor that arises from the secretory tissue that lines the inner cavity of the uterus. The tumors usually arise from the endometrial or inside layers of the uterus.


Reported incidence rates of uterine cancer in rabbits have ranged from 50%-80% in female rabbits over 4 years of age, especially in certain breeds.<ref name="bsava">British Small Animal Veterinary Association, [http://www.bsava.com/Advice/PolicyStatements/NeuteringofRabbits/tabid/162/Default.aspx Policy Statement on the Neutering of Rabbits]</ref> For this reason alone, rescues and veterinarians strongly recommend the [[spaying]] of female non-breeding rabbits.
Reported incidence rates of uterine cancer in rabbits have ranged from 50%-80% in female rabbits over 4 years of age, especially in certain breeds.<ref name="bsava">British Small Animal Veterinary Association, [https://web.archive.org/web/20101031000821/http://www.bsava.com:80/Advice/PolicyStatements/NeuteringofRabbits/tabid/162/Default.aspx Policy Statement on the Neutering of Rabbits]</ref> For this reason alone, rescues and veterinarians strongly recommend the [[spaying]] of female non-breeding rabbits.
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== Symptoms ==
== Symptoms ==
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== Experiences ==
== Experiences ==
Below are some anecdotes about encounters with uterine cancer in rabbits.
Below are some anecdotes about encounters with uterine and other reproductive cancers in rabbits - some operable, some not.
* Great Western Exotic Vets, [http://www.gwexotics.com/exotic-pet-cases/cases-2011/may-2011-uterine-adenocarcinoma-in-a-rabbit.shtml May 2011 - Uterine Adenocarcinoma in a Rabbit]
* Miriam's Bunnies, [http://www.mybunnies.com/onyx_surgery.htm Onyx's Story]
* Rachel Cama-Lekx, [http://www.rabbitnetwork.org/articles/evespay.shtml Eve's Story: The Consequences of Not Spaying]
* RabbitsOnline, [http://www.rabbitsonline.net/f27/uterine-cancer-worried-need-some-advice-64287/ Uterine Cancer ... Worried and Need some Advice]


== Further Reading ==
* u/FurstRoyalty-Ties. (2024). [https://reddit.com/r/Rabbits/comments/1f980pa/today_we_had_to_say_goodbye_to_our_beloved_female/ Elderly female rabbit was euthanized for uterine cancer and a severe infection.] {{RIP}}
* PetMD, [http://www.petmd.com/rabbit/conditions/reproductive/c_rb_uterine_adenocarcinoma#.UHZcbsXA-So Uterine Adenocarcinoma in Rabbits]
* Everybunny Counts Rabbit Rescue. (2024). [https://www.facebook.com/EverybunnyCounts/posts/pfbid02H9HYAhcHfdqDXyeqSkPrqBgk2QKKbAYRWHAnb6wsFdkai5j4SdqYjX7PauWnW1Pjl Aspen's story] {{Graphic}} {{RIP}}
* St. Francis Animal & Bird Hospital Library, [http://www.stfrancisanimalandbird.com/ResourcesLibrary/?page_id=244 Rabbit Uterine Adenocarcinoma]
* Willys Wabbits. (2023). [https://www.facebook.com/permalink.php?story_fbid=pfbid02eDyP1ZunA5pAKNcxFt6oizhpfiWLxqGmXBTc92cSFMV9GzvqUQeH1hhaVYEq1iQfl&id=100064660213050 Zoe's story] {{graphic}}
* Rabbit Welfare Association & Fund, [http://www.rabbitwelfare.co.uk/resources/content/info-sheets/uterine.htm Uterine cancer in the doe: What's the story?]
* Dr. Alisa Rassin. (2022). [https://www.facebook.com/bunnyvetrassin/posts/pfbid026aZ4nifLp94satTYJDtJZY8bPqnjyeEwNdm8Xt1vpDCWrtXSsKEkKUTh6JMu8QJsl Elderly unspayed female rabbit was diagnosed with unoperable metastatic reproductive cancer.] {{RIP}}
* Wildpro, [http://wildpro.twycrosszoo.org/S/00dis/Miscellaneous/UterineAdenocarcinomaRabbit.htm Endometrial Adenocarcinoma and other Uterine Neoplasia in Lagomorphs]
* Lori Mills. (2022). [https://www.facebook.com/princess.tribble/posts/pfbid0qwTXxwZyZYnpWpNzAZzQoCjsYUgpkoEnB5RN8uTYGnnWLRe7b6mMkyEQ5pDZnPNAl A surrendered 10-year-old female rabbit that was euthanized due to multiple cancers all over her stomach area, likely from being unspayed.] {{Graphic}} {{RIP}}
* House Rabbit Society, [http://www.rabbit.org/care/bibliography.html Medical Bibliography]
* u/BronstigHertje. (2022). [https://reddit.com/r/Rabbits/comments/uimaz4/my_bun_died_from_cancer_in_my_arms_how_to_deal/ My bun died from cancer in my arms.] {{RIP}}
* FVMA's 82nd Annual Conference, [http://www.fvmace.org/FVMA%2082nd%20Annual%20Conference/Proceedings/Rabbit%20Neoplasia.html Rabbit Neoplasia]
* u/the57thdoctor. (2022). [https://reddit.com/r/Rabbits/comments/u1nyq2/i_never_posted_carmie_on_here_before_however/ I never posted Carmie on here before. However, recently she was diagnosed with uterine caner. She’s older at 8 & in my opinion deserves to be remembered. Such a behaved bun & unique character/ears.] {{RIP}}
* Vetstream, [http://www.vetstream.com/lapis/Content/Freeform/fre00002.asp Uterine adenocarcinoma]
* u/dubbledubblepls. (2022). [https://reddit.com/r/Rabbits/comments/tjau00/keep_my_baby_cadbury_in_your_thoughts_shes_off_to/ Cadbury's story]
* The Merck Veterinary Manual, [http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/171350.htm Neoplasia]
* Bunny Wonderland. (2021). [https://www.facebook.com/watch/?v=827701151169829 Raichu's story]
* Toni Eisman. (2021). [https://www.facebook.com/groups/houserabbit/posts/10159713114853809/ Onyx and Pyrites' stories]
* The Unusual Pet Vets. (2021). [https://www.facebook.com/TheUnusualPetVets/posts/6301029219937318 Lottie' story] {{graphic}}
* Safe Haven Rabbit Rescue, Inc. (2020). [https://www.safehavenrr.org/heartsforhope Hope's story]
* The Bunny Burrow Rabbit Rescue. (2019). [https://www.facebook.com/thebunnyburrow/photos/a.533195630098053/2348236181927313/ Midna's story]
* u/kingbun7. (2019). [https://reddit.com/r/Rabbits/comments/dv1fbf/im_writing_this_post_to_remember_my_baby_sweetpea/ Sweetpea's story]
* ‎Debbi Braunschweiger‎. (2019). [https://www.facebook.com/groups/houserabbit/permalink/10157436446083809/ Charlotte's story] {{RIP}}
* Bunny Bun Hub. (2019). [https://www.facebook.com/bunnybunhub/posts/427690317924595 Uterine cancer detection]
* Angie Bell. (2019). [https://www.facebook.com/angie.bell.391/posts/3199588630112869 Pictures of uterine cancer] {{graphic}}
* u/octopusbackpack. (2017). [https://reddit.com/r/Rabbits/comments/5fqvtj/my_bunbun_has_uterine_cancer_advice/ My bun-bun has uterine cancer. Advice?]
* Facebook. (2016). [https://www.facebook.com/sweetiesjourney/posts/715497098599192 Sweetie's Journey], [https://www.facebook.com/pg/sweetiesjourney/photos/?tab=album&album_id=736251953190373 Stories about other rabbits that had/have uterine cancer]
* u/Minniebunny. (2014). [https://www.reddit.com/r/Rabbits/comments/2k6ohp/miss_celie_will_live_to_be_an_old_bunny_thanks_to/ Miss Celie will live to be an old bunny, thanks to the /r/rabbits community (more in comments).]
* NYDesi80. (2011). [http://www.rabbitsonline.net/f27/uterine-cancer-worried-need-some-advice-64287/ Uterine Cancer ... Worried and Need some Advice]
* Rachel Cama-Lekx. (2006). [http://www.rabbitnetwork.org/education-resources/articles/rabbit-health-articles/eves-story-the-consequences-of-not-spaying/ Eve's Story: The Consequences of Not Spaying]
* Miriam's Bunnies. (2000). [http://www.mybunnies.com/onyx_surgery.htm Onyx's story]


The following are scientific papers analyzing the statistics of cancer in intact female rabbits.
== Further reading ==
* Harry S. N. Greene, [http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1959.tb44573.x/abstract Adenocarcinoma of the uterine fundus in the rabbit.]
* PetMD. [http://www.petmd.com/rabbit/conditions/reproductive/c_rb_uterine_adenocarcinoma#.UHZcbsXA-So Uterine Adenocarcinoma in Rabbits]
* Theodore H. Ingalls, William M. Adams, Max B. Lurie and Johannes Ipsen, [http://jnci.oxfordjournals.org/content/33/5/799.short Natural History of Adenocarcinoma of the Uterus in the Phipps Rabbit Colony]
* House Rabbit Society. [http://www.rabbit.org/care/bibliography.html Medical Bibliography]
* E. Cotchin, [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071320/ Spontaneous Uterine Cancer in Animals], pg. 216-218
* Vetstream. [https://www.vetstream.com/treat/lapis/freeform/uterine-adenocarcinoma Uterine adenocarcinoma]
* Th. A. M. Elsinghorsa, H. J. F. Timmermans & H. G. Ch. J. M. Hendriks, [http://www.tandfonline.com/doi/abs/10.1080/01652176.1984.9693937 Comparative pathology of endometrial carcinoma]
* Dr Jay E. Hreiz. (2013). [http://msue.anr.msu.edu/uploads/219/38708/Uterine_Adenocarcinoma_in_Rabbits_Jan-Feb_20130001.pdf Uterine Adenocarcinoma in Rabbits]
* Hablolvarid, M.H., Golami, M.R., Moharami, M., [http://www.sid.ir/en/VEWSSID/J_pdf/83520060308.pdf Uterine Adenocarcinoma in a Rabbit]


The following are articles from rabbit breeders presenting a more well-rounded side about uterine cancer in intact does.
The following are scientific papers analyzing the statistics of uterine disorders in intact female rabbits.
* Bucky's Bunny Barn, [http://buckysbunnies.tripod.com/UC.html Uterine Cancer in Rabbits]
* Johanna Mäkitaipale et al. (2022). [https://www.sciencedirect.com/science/article/pii/S1557506322000015 Prospective survey of neoplastic and non-neoplastic uterine disorders in 116 domestic rabbits (<i>Oryctolagus cuniculus</i>)]
* The Bunny Box, [http://thebunnybox.weebly.com/1/post/2013/01/doe-heath-check.html Doe Heath Check]
* Berit Baum. (2021). [https://journals.sagepub.com/doi/abs/10.1177/03009858211002190 Not Just Uterine Adenocarcinoma—Neoplastic and Non-Neoplastic Masses in Domestic Pet Rabbits (<i>Oryctolagus cuniculus</i>): A Review]
* Frank Künzel et al. (2015). [https://meridian.allenpress.com/jaaha/article-abstract/51/1/8/183260/Uterine-Disorders-in-50-Pet-Rabbits Uterine Disorders in 50 Pet Rabbits]
* B. Walter et al. (2010). [https://wabbitwiki.com/images/a/a9/Uterinedisordersin59rabbits.pdf Uterine disorders in 59 rabbits] {{PDF}}
* Kumiko Saito et al. (2002). [https://www.jstage.jst.go.jp/article/jvms/64/6/64_6_495/_article/-char/ja/ Uterine Disorders Diagnosed by Ventrotomy in 47 Rabbits]
* Th. A. M. Elsinghorsa et al. (1984). [http://www.tandfonline.com/doi/abs/10.1080/01652176.1984.9693937 Comparative pathology of endometrial carcinoma]
* Theodore H. Ingalls et al. (1964). [http://jnci.oxfordjournals.org/content/33/5/799.short Natural History of Adenocarcinoma of the Uterus in the Phipps Rabbit Colony]
* E. Cotchin. (1964). [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071320/ Spontaneous Uterine Cancer in Animals]
* Harry S. N. Greene. (1959). [http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1959.tb44573.x/abstract Adenocarcinoma of the uterine fundus in the rabbit.]


The following are some relevant FAQs about uterine cancer in rabbits.
== See also ==
* AllExperts, Dana Krempels, Ph.D., [http://en.allexperts.com/q/Rabbits-703/2008/9/Spay-Uterine-Cancer.htm Spay/Uterine Cancer]
* [[Pyometra]]
* AllExperts, Dana Krempels, Ph.D., [http://en.allexperts.com/q/Rabbits-703/2009/1/Rabbit-bleeding-re-post.htm Rabbits/Rabbit - bleeding (re-post w/added info)]
* [[Spaying and neutering rabbits]]
 
== See Also ==
* [[Spaying and Neutering]]


== References ==
== References ==
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[[Category:Health]]
[[Category:Health]]
[[Category:Reproductive issues]]

Latest revision as of 18:00, 4 September 2024

This article is incomplete because it lacks depth or is unfinished. Help by expanding it.

Uterine cancer, also known as uterine or endometrial adenocarcinoma or uterine neoplasia, is a serious risk for intact female rabbits. Uterine adenocarcinoma is a gland-like malignant type of tumor that arises from the secretory tissue that lines the inner cavity of the uterus. The tumors usually arise from the endometrial or inside layers of the uterus.

Reported incidence rates of uterine cancer in rabbits have ranged from 50%-80% in female rabbits over 4 years of age, especially in certain breeds.[1] For this reason alone, rescues and veterinarians strongly recommend the spaying of female non-breeding rabbits.

Symptoms

Intact female rabbits over 3-4 years of age are most at risk.

  • Blood in urine.
  • Vaginal discharge stained with blood.
  • Cysts in the mammary glands and mammary growths.
  • Cloudy fluid that may come from the mammary glands.
  • Behavioral changes, including aggressiveness.
  • Lethargy, inability to eat, and pale mucous membranes.
  • Abdominal masses

Experiences

Below are some anecdotes about encounters with uterine and other reproductive cancers in rabbits - some operable, some not.

Further reading

The following are scientific papers analyzing the statistics of uterine disorders in intact female rabbits.

See also

References

  1. ↑ British Small Animal Veterinary Association, Policy Statement on the Neutering of Rabbits
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