Hepatic lipidosis

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Hepatic lipidosis, also known as fatty liver disease, liver steatosis, or hepatic steatosis, is characterized by the excess accumulation of fat in the liver. It is usually the end-point of untreated GI stasis.[1]:312 Once hepatic lipidosis is established, fatty infiltration of the kidneys occurs and the rabbit goes into liver and kidney failure.[1]:314


Hepatic lipidosis occurs most readily in obese rabbits because they have already accumulated triglycerides in the hepatocytes and in rabbits fed a high-fat diet.[1]:313 Any rabbit that causes prolonged anorexia can result in fatty infiltration of the liver.[1]:313 Pregnant and lactating rabbits also have an increased risk of developing hepatic lipidosis.[1]:314


Hepatic lipidosis can be prevented in anorexic rabbits by maintaining a positive energy balance with nutritional support and prompt treatment.

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