Hepatic lipidosis, also known as fatty liver disease, liver steatosis, or hepatic steatosis, is characterized by the excess accumulation of fat in the liver. It is usually the end-point of untreated GI stasis.:312 Once hepatic lipidosis is established, fatty infiltration of the kidneys occurs and the rabbit goes into liver and kidney failure.:314
Hepatic lipidosis occurs most readily in obese rabbits because they have already accumulated triglycerides in the hepatocytes and in rabbits fed a high-fat diet.:313 Any rabbit that causes prolonged anorexia can result in fatty infiltration of the liver.:313 Pregnant and lactating rabbits also have an increased risk of developing hepatic lipidosis.:314
Hepatic lipidosis can be prevented in anorexic rabbits by maintaining a positive energy balance with nutritional support and prompt treatment.
- House Rabbit Society. (2013). Liver (Hepatic) Disease in Rabbits
- MediRabbit.com. (n.d.). Case report: hepatic steatosis (fatty liver) in a rabbit
- Wildpro. (n.d.). Hepatic Lipidosis in Rabbits
- Varga, M. (2013). Textbook of rabbit medicine. (2nd ed.).