Leporid herpesvirus 4

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Leporid herpesvirus 4 (LHV-4) is a novel alphaherpesvirus identified in domestic rabbits O. cuniculus.

LHV-4 reports

  • 1990's - Commercial rabbits in Alberta, Saskatchewan, and British Columbia, Canada. Thought to be LHV4.
  • 2008 - Mini Rex and crossbred rabbits in a rabbitry in Alaska. LHV4 affected over half of the 55 rabbits on the premises, and 16 rabbits died or were euthanatized because of illness.
  • 2010 - 1.5-year-old intact female New Zealand white pet rabbit in northern Ontario, Canada. Housed outside in a hutch, passed away.


Affected animals presented with conjunctivitis, subcutaneous swellings, lethargy, respiratory distress, and abortion.[1]

Further reading

See also


  1. Marina L. Brash, Éva Nagy, Yanlong Pei, Susy Carman, Susan Emery, Alec E. Smith, and Patricia V. Turner. (2010). Acute hemorrhagic and necrotizing pneumonia, splenitis, and dermatitis in a pet rabbit caused by a novel herpesvirus (leporid herpesvirus-4).