From WabbitWiki

Snuffles or rhinitis is not a particular disease but a catch-all term for respiratory infections in a rabbit. The most common bacteria that is the cause of snuffles is Pasteurella, but other common causes include staphylococci and Bordetella.


  • Sneezing fits with or without nasal discharge
  • Nasal discharge
  • Staining of the front paws
  • Bleeding from the nose (epistaxis)
  • Wheezing and squeaking sounds while eating
u/sneaky_dragon. (2022). Lop rabbit wheezing from severe nasal infection while eating hay


A lop rabbit with chronic sneezing with and without discharge over a period of 6+ months started suddenly wheezing. Radiographs showed severe mineralization in the nasal cavity (yellow rectangle), likely due to chronic rhinitis. The rabbit was ultimately treated with a rhinotomy to clean out the purulent material blocking the airway because rabbits are obligate nasal breathers and cannot breathe through their mouths.
  • Aerobic bacteria such as Staphylococcus aureus, Bordetella bronchiseptica, Moraxella catarrhalis, Pseudomonas aeruginosa, Mycobacterium spp., and Pasteurella multocida.[1]
  • Anaerobic bacteria such as Fusobacterium nucleatum, Prevotella spp., Peptostreptococcus micros, Actinomyces israelii, and Arcanobacterium haemolyticum.[1]
  • Fungus (mycosis) such as Aspergillus spp. - extremely rare
  • Dental disease
  • Facial trauma
  • Foreign bodies such as inhaled vegetable matter.
  • Allergic or irritant such as inhaled pollen, moldy bedding, dusty hay or litter, or cigarette smoke
  • Cancers (neoplasia) such as squamous cell carcinoma, osteosarcoma, chondrosarcoma, and fibrosarcoma.

Rabbits can also be more prone to snuffles due to stress, concurrent disease or corticosteroid use. Poor husbandry such as dirty molding bedding, ammonia buildup from urine-soaked bedding, dusty cat litter, and cleaning agents can also increase the risk factor of snuffles. Lastly, diets too low in coarse fiber content (long-stemmed hay) can predispose a rabbit to dental disease and consequently snuffles symptoms.[1]


Veterinarians will diagnose simple minor snuffles with a physical examination based on symptoms. Chronic or more severe snuffles will often require further diagnostics with culture and sensitivity testing of discharge, radiographs, and CT scans to find the root cause of the unending infection.


For acute relief, steam therapy (e.g. sitting with rabbit in a steamy bathroom) and humidifiers can help relief congestion. If there is visible mucus outside of the nose, it can be carefully removed with a damp towel or 1cc or baby bulb syringe.

Veterinarians will often first treat an upper respiratory infection (URI) presumptively based on symptoms by prescribing an oral antibiotic. Common choices include enrofloxican, trimethoprim/sulfamethoxazole, doxycycline, marbofloxacin, and azithromycin. In general, if the antibiotic is effective, owners should see a good improvement within 3-5 days.

If the first antibiotic was ineffective, veterinarians may choose to try a different oral antibiotic and evaluate results or proceed with a culture and sensitivity test to figure out the exact strain of bacteria causing the symptoms and an effective antibiotic for it.

If there is still no improvement after choosing an antibiotic with a culture and sensitivity test, further diagnostics such as radiographs and CT scans should be considered to rule out more serious issues such as growths, pus, dental issues, and abscesses causing the chronic infection.

Medication through routes such as penicillin injections and nebulization may also be considered if symptoms are severe.

Allergies may be considered as a diagnosis if all other routes of diagnostics have been inconclusive. However, rabbits with allergies should see marked improvement when prescribed with antihistamines.

Some more resources about treating snuffles in rabbits:


Further reading

See also